王熙 求是科创学者
博士，研究员，“浙大科创百人”
职务：合成生物所 PI
研究方向：生物合成与微生物代谢工程, 生物与信息交叉融合技术
邮箱:xi.wang@zju.edu.cn
地址：杭州市萧山区建设三路733号浙江大学杭州国际科创中心
个人简介：
王熙，博士毕业于美国华盛顿州立大学，后于美国劳伦斯伯克利国家实验室，能源部联合生物能源研究所(Joint BioEnergy Institute)从事博士后研究，长期致力于微生物代谢工程与合成生物学研究，包括生物能源、生物制品的生物合成，计算机辅助生物系统设计与高通量研究平台的开发等。代表成果发表于Metabolic Engineering, Biotechnology Advances等期刊。本课题组重点研究方向为生物合成与微生物代谢工程，生物与信息交叉融合技术(BT-IT) 等。
代表论文：
1.Wang, X., Pereira J. H., Tsutakawa, S., Fang, X., Adams, P. D., Mukhopadhyay, A., Lee, T. S. Efficient production of oxidized terpenoids via engineering P450 fusion proteins. Metabolic Engineering, 2021, 64:41–51.
2.Wang, X., Goh, E., Beller, H. Engineering E. coli for simultaneous glucose-xylose utilization during methyl ketone production. Microbial Cell Factories, 2018, 17:12.
3.Wang, X., Yu, L., Chen, S. UP Finder: A COBRA toolbox extension for identifying gene overexpression strategies for targeted overproduction. Metabolic Engineering Communications,2017, 5:54–59.
4.Wang, X., Xiong, X., Sa, N., Roje, S., Chen, S. Metabolic engineering of enhanced glycerol-3-phosphate synthesis to increase lipid production in Synechocystis sp. PCC 6803. Applied Microbiology and Biotechnology, 2016, 100(13):6091–6101.
5.Li, Y., Wang, X., Ge, X., Tian, P. High production of 3-hydroxypropionic acid in Klebsiella pneumoniae by systematic optimization of glycerol metabolism. Scientific Reports, 2016, 6:26932.
6.Xiong, X., Wang, X., Chen, S. Engineering of an L-arabinose metabolic pathway in Rhodococcus jostii RHA1 for biofuel production. Journal of Industrial Microbiology & Biotechnology, 2016, 43(7):1017–1025.
7.Xiong, X., Wang, X., Chen, S. Engineering of a xylose metabolic pathway in Rhodococcus strains. Applied and Environmental Microbiology, 2012, 78(16):5483–5491.
8.Wang, X., Sa, N., Tian, P., Tan, T. Classifying DNA assembly protocols for devising cellular architectures. Biotechnology Advances, 2011, 29(1):156–163.
专利：
Lee, T. S.,Wang, X. 2021. Fusion proteins useful for modifying terpenes. U.S. Appl. 17/207,097.
