个人简介：陶凯，浙江大学机械工程学院研究员、杭州国际科创中心青年PI；博士毕业于中国石油大学（华东）化学工程与技术专业；并在以色列特拉维夫大学生物科学与技术系开展博士后和高级研究员研究工作。主要从事生物有机（肽）自组装制造及其功能应用、超结构和超组装材料的制备和性能测试、生物有机光电(子)软器件的设计制造、器件集成、先进表征、器件机制以及性能与可靠性优化等研究。

教学工作：《设计与制造I》

研究与成果：

主要从事超分子材料的设计、制备与应用，生物有机（肽）自组装制造、表面微纳功能结构制造、仿生制造，生物有机材料-超结构-软器件一体化，超结构智能装备的设计制造和生物-器件界面交互等研究。具体研究方向包括生物有机（肽）自组装及其功能应用、超结构和超组装材料的制备和性能测试、生物有机光电(子)软器件（压电、二次电池、触觉传感）的设计制造等。研究成果先后发表在Science, Nature Catal., Chem. Soc. Rev., Energy Environ. Sci., Adv. Mater., Mater. Today, Angew. Chemie. Nature Commun.等国际学术期刊。

工作研究项目：

1. 国家自然科学基金面上项目：芳香短肽自组装阵列基PN结光电容器及其应用基础研究（2021-2025，主持）

2. 国家重点研发计划：多肽自组装阵列基仿生电子皮肤的研制（2022-2024，主持）

发表论文：

1. Jiahao Zhang, Sarah Guerin, Haoran Wu, Bin Xue, Yi Cao, Syed A. M. Tofail, Yancheng Wang, Damien Thompson, Wei Wang, Kai Tao, Deqing Mei, Ehud Gazit. Modulating vectored non-covalent interactions for layered assembly with engineerable properties. Bio-des. Manuf., 2022, DOI: 10.1007/s42242-022-00186-3

2. Kai Tao, Asuka A. Orr, Wen Hu, Pandeeswar Makam, Jiahao Zhang, Qiang Geng, Boxin Li, Joseph M. Jakubowski Yancheng Wang, Phanourios Tamamis, Rusen Yang, Deqing Mei, Ehud Gazit. EDTA-Mimic Amino Acid-Metal Ions Coordination for Multifunctional Packings. J. Mater. Chem. A 2021,9, 20385-20394 (Inside Cover)

3. Joseph O’Donnell, Pierre-André Cazade, Sarah Guerin, Ahmed Djeghader, Ehtsham Ul Haq, Kai Tao, Ehud Gazit, Eiichi Fukada, Christophe Silien, Tewfik Soulimane, Damien Thompson, Syed A. M. Tofail. Piezoelectricity of the Transmembrane Protein ba₃ Cytochrome c Oxidase. Adv. Funct. Mater.2021, 2100884.

4. Haotian Lu, Xuanlin Zhang, Minghe Luo, Keshuang Cao, Yunhao Lu, Ben Bin Xu, Hongge Pan, Kai Tao, Yinzhu Jiang. Amino Acid-Induced Interface Charge Engineering Enables Highly Reversible Zn Anode. Adv. Funct. Mater.2021, 2103514.

5. Joseph O’Donnell, Sarah Guerin, Pandeeswar Makam, Pierre-Andre Cazadea, Ehtsham Ul Haq, Kai Tao, Ehud Gazit, Christophe Silien, Tewfik Soulimane, Damien Thompson, Syed A.M. Tofail. Atomistic-Benchmarking towards a protocol development for rapid quantitative metrology of piezoelectric biomolecular materials. Appl. Mater. Today, 2020, 21, 100818.

6. Kai Tao, Bin Xue, Shuyi Han, Ruth Aizen, Linda J. W. Shimon, Zhengyu Xu, Yi Cao, Deqing Mei, Wei Wang, Ehud Gazit. Bioinspired Suprahelical Frameworks as Scaffolds for Artificial Photosynthesis. ACS Appl. Mater. Interfaces 2020, 12, 45192-45201.

7. Kai Tao, Yiming Tang, Sigal Rencus-Lazar, Yifei Yao, Bin Xue, Sharon Gilead, Guanghong Wei, Ehud Gazit. Bioinspired Supramolecular Packing Enables High Thermo-Sustainability. Angew. Chem. Int. Edit. 2020, 132, 19037-19041. (Hot Paper)

8. Yu Chen, Asuka A. Orr, Kai Tao (co-first), Zhibin Wang, Antonella Ruggiero, Linda J. W. Shimon, Lee Schnaider, Alicia Goodall, Sigal Rencus-Lazar, Sharon Gilead, Inna Slutsky, Phanourios Tamamis, Zhan’ao Tan, Ehud Gazit. High-efficiency fluorescence through bioinspired supramolecular self-assembly. ACS Nano 2020, 14, 2798-2807.

9. Kai Tao, Yu Chen, Asuka A. Orr, Zhen Tian, Pandeeswar Makam, Sharon Gilead, Mingsu Si, Sigal Rencus-Lazar, Songnan Qu, Mingjun Zhang, Phanourios Tamamis, Ehud Gazit. Enhanced fluorescence for bioassembly by environment-switching doping of metal ions. Adv. Funct. Mater. 2020, 1909614.

10. Kai Tao, Joseph O' Donnell, Hui Yuan, Ehtsham. U. Haq, Sarah Guerin, Linda J. W. Shimon, Bin Xue, Christophe Silien, Yi Cao, Damien Thompson, Rusen Yang, Syed A. M. Tofail, Ehud Gazit. Accelerated energy transfer in water-layered bioinspired assemblies. Energy Environ. Sci. 2020, 13, 96-101.

11. Yu Chen, Kai Tao, Wei Ji, Pandeeswar Makam, Sigal Rencus-Lazar, Ehud Gazit. Self-assembly of cyclic dipeptides: Diketopiperazines as platforms for functional materials. Protein Pept. Lett. 2020, 27, 688-697 .

12. Vasantha Basavalingappa, Bin Xue, Sigal Rencus-Lazar, Wei Wang, Kai Tao, Yi Cao, Ehud Gazit. Self‐assembled quadruplex‐inspired peptide nucleic acid tetramer for artificial photosynthesis. ChemPhotoChem 2020, 4, 5154-5158.

13. Vasantha Basavalingappa, Santu Bera, Bin Xue, Joseph O’Donnell, Sarah Guerin, Pierre-Andre Cazade, Hui Yuan, Ehtsham ul Haq, Christophe Silien, Kai Tao, Linda J. W. Shimon, Syed A. M. Tofail, Damien Thompson, Sofiya Kolusheva, Rusen Yang, Yi Cao, and Ehud Gazit. Diphenylalanine-derivative peptide assemblies with increased aromaticity exhibit metal-like rigidity and high piezoelectricity. ACS Nano 2020, 14, 7025-7037.

14. Bingbing Sun, Kai Tao (co-first), Yi Jia, Xuehai Yan, Qianli Zou, Ehud Gazit, Junbai Li. Photoactive properties of supramolecular assembled short peptides. Chem. Soc. Rev. 2019, 48, 4387-4400.

15. Kai Tao, Bin Xue, Qi Li, Wen Hu, Linda J. W. Shimon, Pandeeswar Makam, Mingsu Si, Xuehai Yan, Mingjun Zhang, Yi Cao, Rusen Yang, Junbai Li, Ehud Gazit. Stable and Optoelectronic dipeptide assemblies for power harvesting. Mater. Today 2019, 30, 10-16.

16. Kai Tao, Wen Hu, Bin Xue, Drahomir Chovan, Noam Brown, Linda JW Shimon, Oguzhan Maraba, Yi Cao, Syed AM Tofail, Damien Thompson, Junbai Li, Rusen Yang, Ehud Gazit. Bioinspired stable and photoluminescent assemblies for power generation. Adv. Mater. 2019, 31, 1807481.

17. Pandeeswar Makam, Sharma Yamijala, Kai Tao, Linda J. W. Shimon, David S. Eisenberg, Michael R. Sawaya, Bryan M. Wong, Ehud Gazit. Non-proteinaceous hydrolase comprised of phenylalanine metallo-supramolecular amyloid-like structure. Nature Catal. 2019, 2, 977-985. (News & Views: A single amino acid enzyme)

18. Hui Yuan, Peipei Han, Kai Tao, Shuhai Liu, Ehud Gazit, Rusen Yang. Piezoelectric peptide and metabolite materials. Research, 2019, 9025939. (Front Cover)

19. Vasantha Basavalingappa, Santu Bera, Bin Xue, Ido Azuri, Yiming Tang, Kai Tao, Linda JW Shimon, Michael R Sawaya, Sofiya Kolusheva, David S Eisenberg, Leeor Kronik, Yi Cao, Guanghong Wei, Ehud Gazit. Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid. Nature Commun. 2019, 10, 5256.

20. Wei Ji, Chengqian Yuan, Shai Zilberzwige-Tal, Ruirui Xing, Priyadarshi Chakraborty, Kai Tao, Sharon Gilead, Xuehai Yan, Ehud Gazit. Metal-ion modulated structural transformation of amyloid-like dipeptide supramolecular self-assembly. ACS Nano 2019, 136, 7300-7309.

21. Kai Tao, Zhen Fan, Leming Sun, Pandeeswar Makam, Zhen Tian, Mark Ruegsegger, Shira Shaham-Niv, Derek Hansford, Ruth Aizen, Zui Pan, Scott Galster, Jianjie Ma, Fan Yuan, Mingsu Si, Songnan Qu, Mingjun Zhang, Ehud Gazit, Junbai Li. Quantum confined peptide assemblies with tunable visible to near-infrared spectral range. Nature Commun. 2018, 9, 3217. (Peptide Semiconductor Times Are Coming)

22. Ruth Aizen, Kai Tao, Sigal Rencus-Lazar, Ehud Gazit. Functional metabolite assemblies - a review. J. Nanopart. Res. 2018, 20, 125.

23. Kai Tao, Makam Pandeeswar, Ruth Aizen, Ehud Gazit. Self-assembling peptide semiconductors. Science 2017, 358, eaam9756.

24. Kai Tao, Bin Xue, Samuel Frere, Inna Slutsky, Yi Cao, Wei Wang, Ehud Gazit. Multiporous supramolecular microspheres for artificial photosynthesis. Chem. Mater. 2017, 29, 4454–4460.

25. Sílvia Pujals, Kai Tao, Adrià Terradellas, Ehud Gazit, Lorenzo Albertazzi. Studying structure and dynamics of self-assembled peptide nanostructures using fluorescence and super resolution microscopy. Chem. Commun. 2017, 53, 7294-7297.

26. Kai Tao, Aviad Levin, Lihi Adler-Abramovich, Ehud Gazit. Fmoc-modified amino acids and Short peptides: simple bio-inspired building blocks for the fabrication of functional materials. Chem. Soc. Rev. 2016, 45, 3935-3953.

27. Kai Tao, Aviad Levin, Guy Jacoby, Roy Beck, Ehud Gazit. Entropic phase transitions with stable twisted intermediates of bio-inspired self-assembly. Chem. Eur. J. 2016, 22, 15237-15241.

28. Kai Tao, Guy Jacoby, Luba Burlaka, Roy Beck, Ehud Gazit. Design of controllable bio-inspired chiroptic self-assemblies. Biomacromolecules 2016, 17, 2937-2945.

29. Jiqian Wang, Kai Tao (co-first), Peng Zhou, Elias Pambou, Zongyi Li, Hai Xu, Sarah Rogers, Stephen King, Jian R. Lu. Tuning self-assembled morphology of the Aβ(16–22) peptide by substitution of phenylalanine residues. Colloids Surf. B 2016, 147, 116-123.

30. Jiqian Wang, Kai Tao, Yazhen Yang, Liyan Zhang, Dong Wang, Meiwen Cao, Yawei Sun and Daohong Xia. Short peptide mediated self-assembly of platinum nanocrystals with selective spreading property. RSC Adv. 2016, 6, 58099-58105.

31. Kai Tao, Eyal Yoskovitz, Lihi Adler-Abramovich, Ehud Gazit. Optical property modulation of Fmoc group by pH-dependent self-assembly. RSC Adv. 2015, 5, 73914-73918.

32. Kai Tao, Lihi Adler-Abramovich, Ehud Gazit. Controllable phase separation by Boc-modified lipophilic acid as a multifunctional extractant. Sci. Rep. 2014, 17509.

33. Kai Tao, Jiqian Wang, Yanpeng Li, Daohong Xia, Honghong Shan, Hai Xu, Jian R Lu. Short peptide-directed synthesis of one-dimensional platinum nanostructures with controllable morphologies. Sci Rep. 2013, 3, 2565.

34. Kai Tao, Jiqian Wang, Peng Zhou, Chengdong Wang, Hai Xu, Xiubo Zhao, Jian R Lu. Self-assembly of short Aβ(16-22) peptides-the effect of terminal capping and the role of electrostatic interaction. Langmuir 2011, 27, 2723–2730.

35. Kai Tao, Jiqian Wang, Daohong Xia, Hai Xu, Jianren Lu, Honghong Shan. Applications of peptides in noble metal nanoparticles (NMNPs) preparation. Prog. Chem. 2012, 24, 1294-1308.

36. Donghui Jia, Kai Tao, Jiqian Wang, Chengdong Wang, Xiubo Zhao, Mohammed Yaseen, Hai Xu, Guohe Que, John RP Webster, Jian R Lu. Dynamic adsorption and structure of interfacial bilayers adsorbed from lipopeptide surfactants at the hydrophilic silicon/water interface: effect of the headgroup length. Langmuir 2011, 27, 8798–8809.

37. Donghui Jia, Kai Tao, Jiqian Wang, Chengdong Wang, Xiubo Zhao, Mohammed Yaseen, Hai Xu, Guohe Que, John RP Webster, Jian R Lu. Interfacial adsorption of lipopeptide surfactants at the silica/water interface studied by neutron reflection. Soft Matter 2011, 7, 1777-1788.

38. Jiqian Wang, Donghui Jia, Kai Tao, Chengdong Wang, Xiubo Zhao, Mohammed Yaseen, Hai Xu, Guohe Que, John RP Webster, Jian R Lu. Interfacial assembly of lipopeptide surfactants on octyltrimethoxysilane-modified silica surface. Soft Matter 2013, 9, 9684-9691.

39. Jiqian Wang, Gang Meng, Kai Tao, Min Feng, Xiubo Zhao, Zhen Li, Hai Xu, Daohong Xia, Jian R Lu. Immobilization of lipases on alkyl silane modified magnetic nanoparticles: effect of alkyl chain length on enzyme activity. PLoS One 2012, 7, e43478.

40. Xiaoqiang Wang, Congmeng Wu, Kai Tao, Kang Zhao, Jiqian Wang, Hai Xu, Daohong Xia, Honghong Shan, Jian R Lu. Influence of ovalbumin on CaCO3 precipitation during in vitro biomineralization. J. Phys. Chem. B 2010, 114, 5301-5308.

专利成果：

[中国专利]

1. 陶凯 耿强 汪延成 梅德庆.基于肽自组装超分子水凝胶的柔性电子皮肤及其制备方法. 114062467A

2. 陶凯 章家豪 汪延成 梅德庆.鸟嘌呤肽核酸自组装纳米球基光子晶体的声场辅助制备方法. 202111668768.2

3. 陶凯 吴浩然 章家豪 俞滨.一种氨基酸螺旋阵列薄膜及其制备方法. 202210201463.9

4. 汪延成 盘何旻 梅德庆 陶凯 许诚瑶 刘佳薇.基于声表面行波的纳米粒子可控合成反应加速装置及方法. 113198400A

5. 梅德庆 刘海宇 汪延成 余世政 宣凌锋 吴琼 陶凯.陶瓷基催化剂载体的墨水直写式3D打印装置及制造方法. 113426464A

6. 汪延成 盘何旻 翁婉玉 梅德庆 许诚瑶 陶凯.一种基于磁流体重构的声学微粒捕获及轨迹操控方法. 202210165400.2

[国际专利]

7. Kai TAO Sigal LAZAR Sharon GILEAD Ehud GAZIT. BIOINSPIRED HIGHLY THERMO-SUSTAINABLE PACKINGS WITH USES THEREOF. US20220041651A1

8. Ehud GAZIT Kai TAO Yu CHEN Sharon GILEAD Sigal LAZAR Pandeeswar MAKAM. QUANTUM CONFINED PEPTIDE ASSEMBLIES AND USES THEREOF. US20210395312A1

9. GAZIT, Ehud BERA, Santu CHEN, Yu GILEAD, Sharon TAO, Kai LAZAR, Sigal YANG, Rusen MONDAL, Sudipta BASAVALINGAPPA, Vasantha. PIEZOELECTRIC PEPTIDE-BASED MATERIALS AND PIEZOELECTRIC DEVICES CONTAINING SAME. WO2020194304A1/ EP3948272A1