相佳佳，博士，特聘研究员，博士生导师，浙江大学杭州国际科创中心“求是科创学者（科创百人）计划”入选者。2012年获浙江大学高分子材料与工程专业学士学位，2018年获浙江大学生物化工专业博士学位，2009-2021年获浙江大学-斯坦福联合招收博士后项目资助从事博士后研究，2021年9月入职浙江大学杭州国际科创中心。
长期从事生物医用高分子材料、药物递送系统等方面的研究。以（共同）第一作者及通讯作者在Nature Biomedical Engineering，Advanced Materials，Nano Today，Advanced Science，Advanced Drug Delivery Reviews，ACS Applied Materials & Interfaces，Journal of Controlled Release等国际知名期刊发表论文10余篇，权国家发明专利6项，主持博后基金一项，担任Advanced Science等期刊审稿人。
Jiajia Xiang#, Yihuai Shen#, Yifan Zhang#, Xin Liu, Quan Zhou, Zhuxian Zhou, Jianbin Tang, Shiqun Shao*, Youqing Shen*, Multipotent poly(tertiary amine-oxide) micelles for efficient cancer drug delivery. Advanced Science 2022, 2200173.
Jiajia Xiang#, Xin Liu#, Guiping Yuan, Runnan Zhang, Quan Zhou, Tao Xie, Youqing Shen*, Nanomedicine from amphiphilized prodrugs: Concept and clinical translation. Advanced Drug Delivery Reviews 2021, 179, 114027.
Kexin Liu#, Jiajia Xiang#, Guowei Wang, Hongxia Xu, Xiangrui, Liu, Jianbin Tang, Youqing Shen, Zhuxian Zhou*, Linear-dendritic polymer-platinum complexes forming well-defined nanocapsules for acid-responsive drug delivery.ACS Applied Materials & Interfaces 2021, 13, 44028-44040.
Jiajia Xiang#, Peiwen Xing#, Liu Xin, Peihong Shen, Shiqun Shao, Quan Zhou, Zhuxian Zhoua, Jianbin Tang, Youqing Shen*, Hydrogen sulfide-activatable prodrug-backboned block copolymer micelles for delivery of chemotherapeutics. Polymer Chemistry 2021, 12, 4167.
Quan Zhou#, Jiajia Xiang#, Lingqiao Hao, Xiaojie Xu, Zhuxian Zhou, Jianbin Tang, Yuan Ping, Youqing Shen*, Polyplex nanovesicles of single strand oligonucleotides for efficient cytosolic delivery of biomacromolecules. Nano Today 2021, 39, 101221.
Siqin Chen#,Yin Zhong#,Wufa Fan#,Jiajia Xiang#,Guowei Wang,Quan Zhou,Jinqiang Wang,Yu Geng,Rui Sun,Zhen Zhang,Ying Piao,Jianguo Wang,Jianyong Zhuo,Hailin Cong,Haiping Jiang,Jun Ling,Zichen Li,Dingding Yang,Xin Yao,Xiao Xu,Zhuxian Zhou,Jianbin Tang,and Youqing Shen*. Enhanced tumour penetration and prolonged circulation in blood of polyzwitterion–drug conjugates with cell-membrane affinity. Nature Biomedical Engineering 2021, 5, 1019-1037.
Shengjun Xu, Sunbin Ling, Qiaonan Shan, Qianwei Ye, Qifan Zhan, Guangjiang Jiang, Jianyong Zhuo, Binhua Pan, Xue Wen, Tingting Feng, Haohao Lu, Xuyong Wei, Haiyang Xie, Shusen Zheng, Jiajia Xiang*, Youqing Shen, and Xiao Xu*. Self-activated cascade-responsive sorafenib and USP22 shRNA co-delivery system for synergetic hepatocellular carcinoma therapy. Advanced Science 2021, 2003042.
Jiajia Xiang, Yinwen Li*, Yifan Zhang, Guowei Wang, Hongxia Xu, Zhuxian Zhou, Jianbin Tang, and Youqing Shen*. Polyphenol-cisplatin complexation forming core-shell nanoparticles with improved tumor accumulation and dual-responsive drug release for enhanced cancer chemotherapy. Journal of Controlled Release 2021, 330, 992-1003.
Chengyuan Dong#, Quan Zhou#, Jiajia Xiang*, Fusheng Liu*, Zhuxian Zhou*, Youqing Shen. Self-assembly of oxidation-responsive polyethylene glycol-paclitaxel prodrug for cancer chemotherapy. Journal of Controlled Release 2020, 321, 529-539.
Xinchi Jiang#, Jiajia Xiang#, Honghui Wu, Tianyuan Zhang, Danping Zhang, Qianhao Xu, Xiaoli Huang, Xianglei Kong, Jihong Sun, Yulan Hu, Kai Li, Yasuhiko Tabata, Youqing Shen*, and Jianqing Gao*.Neural stem cells transfected with reactive oxygen species–responsive polyplexes for effective treatment of ischemic stroke. Advanced Materials 2019, 31, 1807591.
Jiajia Xiang#, Xin Liu#, Zhuxian Zhou, Dingcheng Zhu, Quan Zhou, Ying Piao, Liming Jiang, Jianbin Tang, Xiangrui Liu, and Youqing Shen*. Reactive oxygen species (ROS)-responsive charge-switchable nanocarriers for gene therapy of metastatic cancer. ACS Applied Materials & Interfaces 2018, 10, 43352-43362.
Jiajia Xiang#, Bihan Wu#, Zhuxian Zhou, Shiqi Hu, Quan Zhou, Guowei Wang, Jianbin Tang, Xiangrui Liu, and Youqing Shen*. Synthesis and evaluation of a paclitaxel-binding polymeric micelle for efficient breast cancer therapy. Science China Life Science 2018, 61, 1-12.
Xin Liu#, Jiajia Xiang#, Dingcheng Zhu, Liming Jiang, Zhuxian Zhou, Jianbin Tang, Xiangrui Liu, Yongzhuo Huang, and Youqing Shen*. Fusogenic reactive oxygen species triggered charge-reversal vector for effective gene delivery. Advanced Materials 2016, 28, 1743-1752.
