张飞研究员本科毕业于重庆大学生物工程学院，博士毕业于浙江大学生命科学研究院，并在徐平龙教授和梁廷波教授的指导下完成博士后训练，入选浙江大学杭州国际科创中心青年卓越人才计划。主要从事病原宿主相互作用研究，建立了戊型肝炎病毒细胞和动物感染模型，提出了靶向病宿互作抗病毒策略，鉴定了戊型肝炎导致纤维化的关键蛋白，揭示了HER2调控核酸免疫识别信号的功能和机制，在PNAS、J Hepatol、Nat Cell Biol、J Biol Chem等杂志发表多篇高水平论文。
(1) Fei Zhang; Ling-Dong Xu; Shiying Wu; Qirou Wu; Ailian Wang; Shengduo Liu; Qian Zhang; Xinyuan Yu; Bin Wang; Yinghao Pan; Fei Huang; Dante Neculai; Bing Xia; Xin-Hua Feng; Li Shen; Tingbo Liang; Yao-Wei Huang; Pinglong Xu;Proteasomal processing of the viral replicase ORF1 facilitates HEV-induced liver fibrosis, PNAS(in press) (共同第一作者 )
(2) Fei Zhang; Ling-Dong Xu; Qian Zhang; Ailian Wang; Xinyuan Yu; Shengduo Liu; Chu Chen;Shiying Wu; Jianping Jin; Aifu Lin; Dante Neculai; Bin Zhao; Xin-Hua Feng; Tingbo Liang; Pinglong Xu; Yao-Wei Huang ; Targeting proteostasis of the HEV replicase to combat infection in preclinical models, Journal of Hepatology, 2023, 78(4): 704-716 (共同第一作者 )
(3) Shiying Wu; Qian Zhang; Fei Zhang; Fansen Meng; Shengduo Liu; Ruyuan Zhou; Qingzhe Wu; Xinran Li; Li Shen; Jun Huang; Jun Qin; Songying Ouyang; Zongping Xia; Hai Song; Xin-Hua Feng; Jian Zou; Pinglong Xu ; HER2 recruits AKT1 to disrupt STING signalling and suppress antiviral defence and antitumour immunity, Nature Cell Biology, 2019, 21(8): 1027-1040 (共同第一作者 )
(4) Fei Zhang; Ling-Dong Xu; Shiying Wu; Bin Wang; Pinglong Xu; Yao-Wei Huang ; Deciphering the hepatitis E virus ORF1: Functional domains, protein processing, and patient-derived mutations, Virology, 2024, 603 (共同第一作者 )
(5) Zhuangzhuang Zhao; Ling-Dong Xu; Fei Zhang; Qi-Zhang Liang; Yajuan Jiao; Fnag-Shu Shi; Biao He; Pinglong Xu; Yao-Wei Huang ; Heat shock protein 90 facilitates SARS-CoV-2 structural protein-mediated virion assembly and promotes virus induced pyroptosis, Journal of Biological Chemistry, 2023, 299(5) (共同第一作者 )
(6) Ling-Dong Xu; Fei Zhang; Chu Chen; Lei Peng; Wen-Ting Luo; Ruiai Chen; Pinglong Xu; Yao Wei Huang ; Revisiting the Mongolian Gerbil Model for Hepatitis E Virus by Reverse Genetics,Microbiology Spectrum, 2022, 10(2): 1-15 (共同第一作者 )
(7) Ling-Dong Xu; Fei Zhang; Lei Peng; Wen-Ting Luo; Chu Chen; Pinglong Xu; Yao-Wei Huang ; Stable Expression of a Hepatitis E Virus (HEV) RNA Replicon in Two Mammalian Cell Lines to Assess Mechanism of Innate Immunity and Antiviral Response, Frontiers in Microbiology, 2020, 11: 1-11 (共同第一作者 )
