利用分子制造技术——以分子作为操纵对象、以分子定义制造模式、以分子调控器件表现，通过从底层对（生物）有机材料的基本构筑单元进行设计和操控，可制造特定形貌与优异性能的功能材料与相应器件装备。分子制造作为生物有机功能新材料和环境友好/生物相容器件装备制造领域的一项变革性技术，可实现从底层构筑基元的设计和操控出发，制备出特定形貌/性能的材料/结构（件），并利用其设计制造面向生物-器件界面交互和智能生物医学工程的功能器件装备。
利用分子制造技术——以分子作为操纵对象、以分子定义制造模式、以分子调控器件表现，通过从底层对（生物）有机材料的基本构筑单元进行设计和操控，可制造特定形貌与优异性能的功能材料与相应器件装备。分子制造作为生物有机功能新材料和环境友好/生物相容器件装备制造领域的一项变革性技术，可实现从底层构筑基元的设计和操控出发，制备出特定形貌/性能的材料/结构（件），并利用其设计制造面向生物-器件界面交互和智能生物医学工程的功能器件装备。
2022年度陆增祺FPTC高科技奖获得者优秀论文奖，2022
浙江大学机械工程学院2021年度优秀德育导师，2022
iCANX2022科学大会优秀论文入围奖，2022
The Marian Gertner Institute for Medical Nanosystems Scholarship (Israel), 2017
The Nanocenter Post-doc scholarship of Tel Aviv University (Israel), 2014
The TÜBİTAK research fellowship program for foreign citizens (Turkey), 2013
中国化学会第十四届胶体与界面化学会议优秀墙报奖，2013
论文发表：
Yunxiao Wang, Qiang Geng, Hao Lyu, Wuxuepeng Sun, Xinyuan Fan, Kang Ma, Kai Wu, Jinhe Wang, Yancheng Wang, Deqing Mei, Chengchen Guo, Peng Xiu, Dingyi Pan, Kai Tao. Bioinspired Flexible Hydrogelation with Programmable Properties for Tactile Sensing. Adv. Mater. 2024, https://doi.org/10.1002/adma.202401678.
Lujing Gao, Zixuan Liu, Daniel Dikovsky, Jiqian Wang, Deqing Mei, Lihi Adler-Abramovich, Ehud Gazit, Kai Tao. Innovation Leading Development: A Glance Towards Bio-3D Printing of Israel. Bio-des. Manuf. 2024, 7, 358-382.
Shuang Chen, Yufan Xia, Ran Zeng, Zhen Luo, Xingxing Wu, Xuzhi Hu, Jian R. Lu, Ehud Gazit, Hongge Pan, Zijian Hong, Mi Yan, Kai Tao, Yinzhu Jiang. Ordered planar plating/stripping enables deep cycling zinc metal batteries. Sci. Adv. 2024, 10, eadn2265.
Kai Tao, Haoran Wu, Lihi Adler-Abramovich, Jiahao Zhang, Xinyuan Fan, Yunxiao Wang, Yan Zhang, Syed A. M. Tofail, Deqing Mei, Junbai Li, Ehud Gazit. Aromatic Short Peptide Architectonics: Assembly and Engineering. Prog. Mater. Sci. 2024, 142, 101240.
Xuzhi Hu, Mingrui Liao, Ke Ding, Jiqian Wang, Hai Xu, Kai Tao, Feng Zhou, Jian R. Lu. Neutron Reflection and Scattering in Characterising Peptide Assemblies. Adv. Colloid Interfac. 2023, 322, 103033.
Yang Li, Ranran Zhang, Fei Wen, Mingchao Li, Wenjun Li, Lili Li, Yang Zhou, Sigal Rencus-Lazar, Kai Tao, Ehud Gazit, Wei Wu, Zhihua Ying, Gaofeng Wang. Bioinspired Supramolecular Arrayed Heterojunction-Based Room-Temperature Sensor for High-Performance Gas Detection. Sens. Actuators B Chem 2023, 396, 134641.
Zhen Luo, Yufan Xia, Shuang Chen, Xingxing Wu, Ran Zeng, Xuan Zhang, Hongge Pan, Mi Yan, Tingting Shi, Kai Tao, Ben Bin XU, Yinzhu Jiang. Synergistic “Anchor-Capture” Enabled by Amino and Carboxyl for Constructing Robust Interface of Zn Anode. Nano-Micro Lett. 2023, 15, 205.
Yan Zhang, Qi Li, Haoran Wu, Yancheng Wang, Yan Wang, Sigal Rencus-Lazar, Yurong Zhao, Jiqian Wang, Deqing Mei, Hai Xu, Ehud Gazit, Kai Tao. Racemic Amino Acid Assembly Enables Supramolecular β-Sheet Transition with Property Modulations. ACS Nano, 2023, 17, 2737–2744.
Yunxiao Wang, Qiang Geng, Yan Zhang, Lihi Adler-Abramovich, Xinyuan Fan, Deqing Mei, Ehud Gazit, Kai Tao. Fmoc-diphenylalanine gelating nanoarchitectonics: A simplistic peptide self-assembly to meet complex applications. J. Colloid Interf. Sci., 2023, 636, 113-133. (Cover)
Jiahao Zhang, Yan Zhang, Yancheng Wang, Sigal Rencus-Lazar, Deqing Mei, Ehud Gazit, Kai Tao. Bio-organic adaptive photonic crystals enable supramolecular solvatochromism. Nano Res., 2023, 16, 12092-12097.
Lingfeng Xuan, Yancheng Wang, Jinwei Lan, Kai Tao, Caiying Zhou, Deqing Mei. Development of cathode ordered membrane electrode assembly based on TiO2 nanowire array and ultrasonic spraying. Energy, 2023, 264, 126243.
Yang Li, Xingyuan Song, Lili Li, Wei Wu, Kai Tao, Zhihua Ying, Yongqian Hu, Yang Zhou, Ranran Zhang, Gaofeng Wang, Fei Wen. Low concentration CO gas sensor constructed from MoS2 nanosheets dispersed SnO2 nanoparticles at room temperature under UV light. Ceram. Int., 2022, DOI: 10.1016/j.ceramint.2022.11.204.
Yu Chen, Kai Tao, Wei Ji, Vijay Bhooshan Kumar, Sigal Rencus-Lazar, Ehud Gazit. Histidine as a key modulator of molecular self-assembly: Peptide-based supramolecular materials inspired by biological systems. Mater. Today, 2022, 60, 106-127.
Jiahao Zhang, Yancheng Wang, Brian J. Rodriguez, Rusen Yang, Bin Yu, Deqing Mei, Junbai Li, Kai Tao, Ehud Gazit. Microfabrication of peptide self-assemblies: inspired by nature towards applications. Chem. Soc. Rev., 2022, 51, 6936-6947.
Jiahao Zhang, Sarah Guerin, Haoran Wu, Bin Xue, Yi Cao, Syed A. M. Tofail, Yancheng Wang, Damien Thompson, Wei Wang, Kai Tao, Deqing Mei, Ehud Gazit. Modulating vectored non-covalent interactions for layered assembly with engineerable properties. Bio-des. Manuf., 2022, 5, 529-539.
Kai Tao, Asuka A. Orr, Wen Hu, Pandeeswar Makam, Jiahao Zhang, Qiang Geng, Boxin Li, Joseph M. Jakubowski Yancheng Wang, Phanourios Tamamis, Rusen Yang, Deqing Mei, Ehud Gazit. EDTA-Mimic Amino Acid-Metal Ions Coordination for Multifunctional Packings. J. Mater. Chem. A 2021, 9, 20385-20394 (Cover)
Joseph O’Donnell, Pierre-André Cazade, Sarah Guerin, Ahmed Djeghader, Ehtsham Ul Haq, Kai Tao, Ehud Gazit, Eiichi Fukada, Christophe Silien, Tewfik Soulimane, Damien Thompson, Syed A. M. Tofail. Piezoelectricity of the Transmembrane Protein ba3 Cytochrome c Oxidase. Adv. Funct. Mater. 2021, 2100884.
Haotian Lu, Xuanlin Zhang, Minghe Luo, Keshuang Cao, Yunhao Lu, Ben Bin Xu, Hongge Pan, Kai Tao, Yinzhu Jiang. Amino Acid-Induced Interface Charge Engineering Enables Highly Reversible Zn Anode. Adv. Funct. Mater. 2021, 2103514.
Joseph O’Donnell, Sarah Guerin, Pandeeswar Makam, Pierre-Andre Cazadea, Ehtsham Ul Haq, Kai Tao, Ehud Gazit, Christophe Silien, Tewfik Soulimane, Damien Thompson, Syed A.M. Tofail. Atomistic-Benchmarking towards a protocol development for rapid quantitative metrology of piezoelectric biomolecular materials. Appl. Mater. Today, 2020, 21, 100818.
Kai Tao, Bin Xue, Shuyi Han, Ruth Aizen, Linda J. W. Shimon, Zhengyu Xu, Yi Cao, Deqing Mei, Wei Wang, Ehud Gazit. Bioinspired Suprahelical Frameworks as Scaffolds for Artificial Photosynthesis. ACS Appl. Mater. Interfaces 2020, 12, 45192-45201.
Kai Tao, Yiming Tang, Sigal Rencus-Lazar, Yifei Yao, Bin Xue, Sharon Gilead, Guanghong Wei, Ehud Gazit. Bioinspired Supramolecular Packing Enables High Thermo-Sustainability. Angew. Chem. Int. Edit. 2020, 132, 19037-19041. (Hot Paper)
Yu Chen, Asuka A. Orr, Kai Tao (co-first), Zhibin Wang, Antonella Ruggiero, Linda J. W. Shimon, Lee Schnaider, Alicia Goodall, Sigal Rencus-Lazar, Sharon Gilead, Inna Slutsky, Phanourios Tamamis, Zhan’ao Tan, Ehud Gazit. High-efficiency fluorescence through bioinspired supramolecular self-assembly. ACS Nano 2020, 14, 2798-2807.
Kai Tao, Yu Chen, Asuka A. Orr, Zhen Tian, Pandeeswar Makam, Sharon Gilead, Mingsu Si, Sigal Rencus-Lazar, Songnan Qu, Mingjun Zhang, Phanourios Tamamis, Ehud Gazit. Enhanced fluorescence for bioassembly by environment-switching doping of metal ions. Adv. Funct. Mater. 2020, 1909614.
Kai Tao, Joseph O' Donnell, Hui Yuan, Ehtsham. U. Haq, Sarah Guerin, Linda J. W. Shimon, Bin Xue, Christophe Silien, Yi Cao, Damien Thompson, Rusen Yang, Syed A. M. Tofail, Ehud Gazit. Accelerated energy transfer in water-layered bioinspired assemblies. Energy Environ. Sci. 2020, 13, 96-101.
Yu Chen, Kai Tao, Wei Ji, Pandeeswar Makam, Sigal Rencus-Lazar, Ehud Gazit. Self-assembly of cyclic dipeptides: Diketopiperazines as platforms for functional materials. Protein Pept. Lett. 2020, 27, 688-697 .
Vasantha Basavalingappa, Bin Xue, Sigal Rencus-Lazar, Wei Wang, Kai Tao, Yi Cao, Ehud Gazit. Self‐assembled quadruplex‐inspired peptide nucleic acid tetramer for artificial photosynthesis. ChemPhotoChem 2020, 4, 5154-5158.
Vasantha Basavalingappa, Santu Bera, Bin Xue, Joseph O’Donnell, Sarah Guerin, Pierre-Andre Cazade, Hui Yuan, Ehtsham ul Haq, Christophe Silien, Kai Tao, Linda J. W. Shimon, Syed A. M. Tofail, Damien Thompson, Sofiya Kolusheva, Rusen Yang, Yi Cao, and Ehud Gazit. Diphenylalanine-derivative peptide assemblies with increased aromaticity exhibit metal-like rigidity and high piezoelectricity. ACS Nano 2020, 14, 7025-7037.
Bingbing Sun, Kai Tao (co-first), Yi Jia, Xuehai Yan, Qianli Zou, Ehud Gazit, Junbai Li. Photoactive properties of supramolecular assembled short peptides. Chem. Soc. Rev. 2019, 48, 4387-4400.
Kai Tao, Bin Xue, Qi Li, Wen Hu, Linda J. W. Shimon, Pandeeswar Makam, Mingsu Si, Xuehai Yan, Mingjun Zhang, Yi Cao, Rusen Yang, Junbai Li, Ehud Gazit. Stable and Optoelectronic dipeptide assemblies for power harvesting. Mater. Today 2019, 30, 10-16.
Kai Tao, Wen Hu, Bin Xue, Drahomir Chovan, Noam Brown, Linda JW Shimon, Oguzhan Maraba, Yi Cao, Syed AM Tofail, Damien Thompson, Junbai Li, Rusen Yang, Ehud Gazit. Bioinspired stable and photoluminescent assemblies for power generation. Adv. Mater. 2019, 31, 1807481.
Pandeeswar Makam, Sharma Yamijala, Kai Tao, Linda J. W. Shimon, David S. Eisenberg, Michael R. Sawaya, Bryan M. Wong, Ehud Gazit. Non-proteinaceous hydrolase comprised of phenylalanine metallo-supramolecular amyloid-like structure. Nature Catal. 2019, 2, 977-985. (News & Views: A single amino acid enzyme)
Hui Yuan, Peipei Han, Kai Tao, Shuhai Liu, Ehud Gazit, Rusen Yang. Piezoelectric peptide and metabolite materials. Research, 2019, 9025939. (Cover)
Vasantha Basavalingappa, Santu Bera, Bin Xue, Ido Azuri, Yiming Tang, Kai Tao, Linda JW Shimon, Michael R Sawaya, Sofiya Kolusheva, David S Eisenberg, Leeor Kronik, Yi Cao, Guanghong Wei, Ehud Gazit. Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid. Nature Commun. 2019, 10, 5256.
Wei Ji, Chengqian Yuan, Shai Zilberzwige-Tal, Ruirui Xing, Priyadarshi Chakraborty, Kai Tao, Sharon Gilead, Xuehai Yan, Ehud Gazit. Metal-ion modulated structural transformation of amyloid-like dipeptide supramolecular self-assembly. ACS Nano 2019, 136, 7300-7309.
Kai Tao, Zhen Fan, Leming Sun, Pandeeswar Makam, Zhen Tian, Mark Ruegsegger, Shira Shaham-Niv, Derek Hansford, Ruth Aizen, Zui Pan, Scott Galster, Jianjie Ma, Fan Yuan, Mingsu Si, Songnan Qu, Mingjun Zhang, Ehud Gazit, Junbai Li. Quantum confined peptide assemblies with tunable visible to near-infrared spectral range. Nature Commun. 2018, 9, 3217. (Peptide Semiconductor Times Are Coming)
Ruth Aizen, Kai Tao, Sigal Rencus-Lazar, Ehud Gazit. Functional metabolite assemblies - a review. J. Nanopart. Res. 2018, 20, 125.
Kai Tao, Makam Pandeeswar, Ruth Aizen, Ehud Gazit. Self-assembling peptide semiconductors. Science 2017, 358, eaam9756.
Kai Tao, Bin Xue, Samuel Frere, Inna Slutsky, Yi Cao, Wei Wang, Ehud Gazit. Multiporous supramolecular microspheres for artificial photosynthesis. Chem. Mater. 2017, 29, 4454–4460.
Sílvia Pujals, Kai Tao, Adrià Terradellas, Ehud Gazit, Lorenzo Albertazzi. Studying structure and dynamics of self-assembled peptide nanostructures using fluorescence and super resolution microscopy. Chem. Commun. 2017, 53, 7294-7297.
Kai Tao, Aviad Levin, Lihi Adler-Abramovich, Ehud Gazit. Fmoc-modified amino acids and Short peptides: simple bio-inspired building blocks for the fabrication of functional materials. Chem. Soc. Rev. 2016, 45, 3935-3953.
Kai Tao, Aviad Levin, Guy Jacoby, Roy Beck, Ehud Gazit. Entropic phase transitions with stable twisted intermediates of bio-inspired self-assembly. Chem. Eur. J. 2016, 22, 15237-15241.
Kai Tao, Guy Jacoby, Luba Burlaka, Roy Beck, Ehud Gazit. Design of controllable bio-inspired chiroptic self-assemblies. Biomacromolecules 2016, 17, 2937-2945.
Jiqian Wang, Kai Tao (co-first), Peng Zhou, Elias Pambou, Zongyi Li, Hai Xu, Sarah Rogers, Stephen King, Jian R. Lu. Tuning self-assembled morphology of the Aβ(16–22) peptide by substitution of phenylalanine residues. Colloids Surf. B 2016, 147, 116-123.
Jiqian Wang, Kai Tao, Yazhen Yang, Liyan Zhang, Dong Wang, Meiwen Cao, Yawei Sun and Daohong Xia. Short peptide mediated self-assembly of platinum nanocrystals with selective spreading property. RSC Adv. 2016, 6, 58099-58105.
Kai Tao, Eyal Yoskovitz, Lihi Adler-Abramovich, Ehud Gazit. Optical property modulation of Fmoc group by pH-dependent self-assembly. RSC Adv. 2015, 5, 73914-73918.
Kai Tao, Lihi Adler-Abramovich, Ehud Gazit. Controllable phase separation by Boc-modified lipophilic acid as a multifunctional extractant. Sci. Rep. 2014, 17509.
Kai Tao, Jiqian Wang, Yanpeng Li, Daohong Xia, Honghong Shan, Hai Xu, Jian R Lu. Short peptide-directed synthesis of one-dimensional platinum nanostructures with controllable morphologies. Sci Rep. 2013, 3, 2565.
Kai Tao, Jiqian Wang, Peng Zhou, Chengdong Wang, Hai Xu, Xiubo Zhao, Jian R Lu. Self-assembly of short Aβ(16-22) peptides-the effect of terminal capping and the role of electrostatic interaction. Langmuir 2011, 27, 2723–2730.
Kai Tao, Jiqian Wang, Daohong Xia, Hai Xu, Jianren Lu, Honghong Shan. Applications of peptides in noble metal nanoparticles (NMNPs) preparation. Prog. Chem. 2012, 24, 1294-1308.
Donghui Jia, Kai Tao, Jiqian Wang, Chengdong Wang, Xiubo Zhao, Mohammed Yaseen, Hai Xu, Guohe Que, John RP Webster, Jian R Lu. Dynamic adsorption and structure of interfacial bilayers adsorbed from lipopeptide surfactants at the hydrophilic silicon/water interface: effect of the headgroup length. Langmuir 2011, 27, 8798–8809.
Donghui Jia, Kai Tao, Jiqian Wang, Chengdong Wang, Xiubo Zhao, Mohammed Yaseen, Hai Xu, Guohe Que, John RP Webster, Jian R Lu. Interfacial adsorption of lipopeptide surfactants at the silica/water interface studied by neutron reflection. Soft Matter 2011, 7, 1777-1788.
Jiqian Wang, Donghui Jia, Kai Tao, Chengdong Wang, Xiubo Zhao, Mohammed Yaseen, Hai Xu, Guohe Que, John RP Webster, Jian R Lu. Interfacial assembly of lipopeptide surfactants on octyltrimethoxysilane-modified silica surface. Soft Matter 2013, 9, 9684-9691.
Jiqian Wang, Gang Meng, Kai Tao, Min Feng, Xiubo Zhao, Zhen Li, Hai Xu, Daohong Xia, Jian R Lu. Immobilization of lipases on alkyl silane modified magnetic nanoparticles: effect of alkyl chain length on enzyme activity. PLoS One 2012, 7, e43478.
Xiaoqiang Wang, Congmeng Wu, Kai Tao, Kang Zhao, Jiqian Wang, Hai Xu, Daohong Xia, Honghong Shan, Jian R Lu. Influence of ovalbumin on CaCO3 precipitation during in vitro biomineralization. J. Phys. Chem. B 2010, 114, 5301-5308.
著作：
Yan Zhang, Jiahao Zhang, Junbai Li, Ehud Gazit, Kai Tao. Minimalistic Peptide Assemblies for Sustainable Optoelectronics. Peptide Self‐Assembly and Engineering: Fundamentals, Structures, and Applications (1st ed.), Wiley‐VCH GmbH, 2024, 241-261.
Haoran Wu, Sarah Guerin, Syed A. M. Tofail, Rusen Yang, Ehud Gazit, Damien Thompson, Kai Tao. Piezoelectric Self-assembling Peptides for Engineering Applications. Peptide Self‐Assembly and Engineering: Fundamentals, Structures, and Applications (1st ed.), Wiley‐VCH GmbH, 2024, 367-392.
专利/著作权成果：
陶凯，耿强，汪延成，梅德庆. 基于肽自组装超分子水凝胶的柔性电子皮肤及其制备方法. 专利号：ZL 2021 1 1067910.8
陶凯，吴浩然，章家豪，俞滨. 一种氨基酸螺旋阵列薄膜及其制备方法. 专利号：ZL 2022 1 0201463.9
陶凯，吴浩然，姜宏博，梅德庆. 双向负载集成的压电性能测试分析软件. 登记号：2023SR0985029
汪延成，盘何旻，梅德庆，陶凯，许诚瑶，刘佳薇. 基于声表面行波的纳米粒子可控合成反应加速装置及方法. 专利号：ZL 2021 1 0484101.0
梅德庆，刘海宇，汪延成，余世政，宣凌锋，吴琼，陶凯. 陶瓷基催化剂载体的墨水直写式3D打印装置及制造方法. 专利号：ZL 2021 1 0776847.9
汪延成，盘何旻，翁婉玉，梅德庆，许诚瑶，陶凯. 一种基于磁流体重构的声学微粒捕获及轨迹操控方法. 专利号：ZL 2022 1 0165400.2
陶凯 章家豪 汪延成 梅德庆. 鸟嘌呤肽核酸自组装纳米球基光子晶体的声场辅助制备方法. 申请号：202111668768.2
Kai Tao, Haoran Wu, Jiahao Zhang, Bin Yu. Amino Acid Helical Array Film and Preparation Method Thereof. 申请号：US18117016
陶凯 吴浩然 姜宏博. 一种双向负载集成的压电性能测试装置. 申请号：202310099468.X
陶凯 姜宏博 吴浩然 梅德庆. 一种压电薄膜及其应用. 申请号：202310791003.0
陶凯 范新媛 章家豪 梅德庆. 一种基于物理气相沉积技术的肽薄膜蒸镀设备及方法. 申请号：202310590362.X
陶凯 曾然 马康. 一种短肽自组装超分子水凝胶电解质及其制备方法、以及二次锌离子电池. 申请号：202310789121.8
陶凯 马康 曾然. 一种可穿戴柔性锌离子电池及其制备方法. 申请号：2023118235443
陶凯 林颂智 李冲 徐世轩. 一种柔性超声换能器阵列及其制备方法. 申请号：2024102026298
项目：
国家重点研发计划：芳香短肽自组装阵列基压电式仿生电子皮肤的研制 主持
国家自然科学基金面上项目：芳香短肽自组装阵列基PN结光电容器及其应用基础研究 主持
